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571190-30-2
编号 CA10003
化学名称Palbociclib
英文名称 Palbociclib
MDL MFCD11840850
分子式 C24H29N7O2
分子量 447.5327
化学名称 : Palbociclib
CAS : 571190-30-2
英文名称: Palbociclib
英文同义词: 6-acetyl-8-cyclopentyl-5-methyl-2-{[5-(piperazin-1-yl)pyridin-2-yl]amino}-7H,8H-pyrido[2,3-d]pyrimidin-7-one
同义词: 6-acetyl-8-cyclopentyl-5-methyl-2-{[5-(piperazin-1-yl)pyridin-2-yl]amino}-7H,8H-pyrido[2,3-d]pyrimidin-7-one
Palbociclib (PD-0332991) is an orally available pyridopyrimidine-derived cyclin-dependent kinase (CDK) inhibitor with potential antineoplastic activity. Palbociclib is a highly specific inhibitor of cyclindependent kinase 4 (Cdk4) (IC50, 0.011 μmol/L) and Cdk6 (IC50, 0.016 μmol/L), having no activity against a panel of 36 additional protein kinases.
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![2-chloro-8-cyclopentyl-5-methylpyrido[2,3-d]pyrimidin-7(8H)-one](http://structure.chemcd.cn/coresyn/structure/CM14178.png)
2-chloro-8-cyclopentyl-5-methylpyrido[2,3-d]pyrimidin-7(8H)-one
1013916-37-4
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OTAVA-BB 1207229
571188-59-5
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tert-butyl 4-(6-nitropyridin-3-yl)piperazine-1-carboxylate
571189-16-7
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![6-bromo-2-chloro-8-cyclopentyl-5-methylpyrido[2,3-d]pyrimidin-7(8H)-one](http://structure.chemcd.cn/coresyn/structure/CM14179.png)
6-bromo-2-chloro-8-cyclopentyl-5-methylpyrido[2,3-d]pyrimidin-7(8H)-one
1016636-76-2
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